The aim of this study was to examine the combined contributions made by anti-femininity, gender role conflict (GRC), and sexual orientation (grouped heterosexual and non-heterosexual), to genderism and social dominance orientation (SDO) in a sample of Irish males. A correlational design was employed and 183 male participants completed self-report measures in an online questionnaire. Overall, results showed anti-femininity to be the stronger predictor of genderism and SDO. GRC did not have a significant partial effect on genderism. GRC did have a significant partial effect on SDO, with anti-femininity making the larger contribution. Sexual orientation had a significant partial effect on genderism, with results showing anti-femininity to be the stronger predictor. Results suggest that attitudes toward femininity are important to consider in the GRC, genderism, and SDO research domains, with conclusions drawn from the results suggesting potential implications for the role of anti-femininity in the socialisation of the male gender role.