The WHO has identified an impending global shortfall of 9 million nursing staff within the next decade. This research aims to investigate stress in the nursing profession with the intention of informing retention focused interventions in the nursing sector. Online surveys containing measures dealing with stress, sleep and personality were distributed via social media. A total of 362 valid responses were obtained. There was a significant relationship between stress and sleep which was mediated, in part, by respondents scores on a brief neuroticism scale. Future nursing retention interventions should focus on sleep hygiene and, ideally, would be personological catered for nurses at higher risk of turnover.